A team of 19 UK scientists has published new research that helps explain why countries with the highest vaccination rates experience the highest numbers of what they call “breakthrough infections” as well as re-infection with other variants of COVID-19.
This research paper, published on June 14, 2022 in the peer-reviewed journal Science, has been downloaded almost 277,500 times in less than two months. This is very unusual for a densely worded highly technical scientific study.
We can only guess the reason so many people read it. But what this study suggests—which many clinicians and researchers have expressed concern about—is that mRNA vaccines against COVID-19, as well as booster shots, may make our immune response less effective against the Omicron variant of the virus.
If this is true, it means that the vaccine itself leads to widespread infection. Instead of stopping the virus, it appears that mRNA vaccination programs around the world may have inadvertently made the virus more ubiquitous.
Higher vaccine uptake leads to higher infection rates
As the British scientists point out, countries with higher vaccine uptake rates experience a high number of primary infections and frequent re-infections with SARS-CoV-2.
In contrast, in places where vaccine campaigns have not been widely implemented – including most countries on the African continent – people do not become infected.
In analyzing why the most vaccinated populations get the most Omicron infections, this study focused on the most vaccinated professionals: Medical personnel who were given the two doses of mRNA vaccines at baseline and then were given booster vaccines two more times . To understand what was happening at the cellular level to these highly vaccinated healthcare workers, the scientists closely monitored the different types of immunoglobin in the blood of the participants.
Immunoglobin (Ig), also known as antibody (Ab), detects viruses, bacteria, and the like and causes the immune system to respond appropriately.
Scientists have identified several types of immunoglobulins, each of which directs the immune response differently for different phases and types of infection.
IgG4, tolerant immune response
IgG4 is the form of immunoglobin that activates a tolerance response in the immune system for things you’ve been exposed to repeatedly and don’t need to trigger an inflammatory response. This is good if you’re trying to avoid immune food sensitivities, for example. But that’s not the kind of immune response that the COVID-19 vaccines are designed to create.
Beekeepers, when repeatedly stung by bees throughout their career, mount an IgG4 response to the attack on their immune system. Basically, their bodies learn that the bee venom is not dangerous and their immune response to the bee venom becomes an IgG4 response, so they can tolerate the stings very well. While the bee venom itself will not harm the body, the body’s own inflammatory response can be dangerous. If the body overreacts and develops a generalized response where the inflammation itself threatens the person’s breathing, the immune response can be deadly.
More vaccines lead to more COVID-19 infections
This study demonstrates exactly how repeated vaccinations make people more susceptible to COVID-19. The initial doses of the vaccine produced classic inflammatory immune responses. Inflammation is a major part of the immune response (to a vaccine or infection) and is responsible for most of what you feel when you are sick: fever, aches, lethargy, etc. This inflammation is why you might feel sick if you get a flu shot, and why the COVID-19 vaccine has become notorious for making people feel so sick for a few days. Your body produces an inflammatory response to the proteins of COVID-19.
But what happens in the body after you’ve had two shots and then you’re given a third? The scientists found that successive doses of the mRNA vaccines began to habituate, or desensitize, subjects to the COVID-19 proteins, shifting their immune response to an IgG4-dominated form, essentially teaching the body to tolerate the proteins.
A different kind of protection?
The participants’ response to COVID-19 was actually turned off, making them even more vulnerable to infection and less likely to respond to it than those who had never been vaccinated.
When you’re exposed to a cold or other virus repeatedly, over a lifetime, which happens with natural exposure, you don’t develop a tolerance to it, your body fights it without you knowing. Your body uses the normal immune response to fight the disease, but because it recognizes the infectious agent, you don’t get symptoms of inflammation. Therefore, when you are naturally exposed to many diseases, you have lifelong immunity.
In contrast, this new study shows that repeated injections of COVID-19 mRNA and boosters induce a tolerance response as if they were allergy shots. They accustom the body to the virus so that it no longer recognizes it as something dangerous.
Another study published in July by a team of more than 20 German scientists independently confirmed that sequential injections and boosters against COVID-19 convert the immune response from a protective class of IgG response to a class of tolerance.
At the same time, the creation of this vaccine-induced tolerance does not mean that subjects are left unprotected.
Caring for sick people
So the vaccine and booster program ended up doing the opposite of what it was intended to do: protect people from disease.
But was that ever a realistic goal? COVID-19 is like related endemic coronaviruses. Just like the common cold, it appears that SARS-CoV-2 will not go away, that no one can avoid it indefinitely, and that it will continue to mutate.
For one thing, this study suggests that vaccines help the body’s immune system not overreact to the virus. The virus itself didn’t kill people—the interaction of the virus with the patients’ immune systems caused severe and sometimes fatal infections as the immune system overreacted to a new virus.
On the other hand, naturally acquired immunity appears to be stronger than vaccine-acquired immunity, and the dangers of the vaccines themselves, especially for young people, suggest that the risks of vaccination far outweigh the benefits.
If vaccinees are already easily infected with the virus but have only mild reactions because their immune system tells them to tolerate it, it may have been beneficial for the vaccination.
But booster shots were never necessary to achieve tolerance: the study showed that subjects began to develop tolerance after just two doses. Vaccines may have helped to desensitize the population to harmful inflammatory immune responses to COVID-19. They have played their part. No need to continue with consecutive boosters.
The views expressed in this article are the opinions of the author and do not necessarily reflect the views of The Epoch Times. Epoch Health welcomes professional discussion and friendly debate. To submit feedback, please follow these instructions and submit it via our form here.