Science builds the compound’s potential for healthy aging

Four months of taking Urolitin A supplements from the Mitopure brand from Amazentis also led to 12% improvements in muscle strength, according to scientists from Amazentis SA, KGK Science and Ecole Polytechnique Fédérale de Lausanne in Cell Reports Medicine.

“These findings are based on previous clinical evidence [urolithin A] and its use as a nutritional intervention to maintain muscle health and promote healthy aging “, they wrote.

The ingredient

Urolithin A is a compound generated by the intestinal microflora from elagitannins found in foods such as pomegranate. The compounds are hydrolyzed in the stomach to ellagic acid, which is subsequently converted from the intestinal microflora to urolithin A. make the metabolite.

As previously reported by NutraIngredients-USA, Amazentis has developed a method for delivering finely calibrated doses of urolithin A. Preliminary data published in Natural medicineshow that urolithin A can improve mitochondrial function by stimulating mitophagy, a process by which damaged mitochondria are recycled to allow renewal with healthy mitochondria.

These powerful beneficial effects have been observed in various organisms, incl C. elegansMammalian, rodent cells and several human clinical trials.

The new study is funded by the Swiss-based Amazentis SA.

Details of the study

The new study included almost 90 healthy middle-aged overweight adults who were randomly assigned to one of three groups: 500 mg Mitopure, 1000 mg Mitopure or placebo over four months.

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