IVF in vitro fertilization (IVF) is a common infertility treatment option used in assisted reproductive technology (ART). This method of conception has gained great popularity among patients and medical professionals over the past few decades and is now more affordable and accessible in low- and middle-income countries.
According to a study, the IVF treatments market in India was valued at USD 478.2 million in 2018 and is expected to grow to USD 1453.0 million by 2026 at a CAGR of 14.7%. This shows that the Indian IVF market is on the way to recovery and seems to have a promising future. Even the government is providing assistance due to the rapid pace of expansion. The Assisted Reproductive Technology Bill (Regulation), which Parliament has just passed, promises high quality, regulation and transparency of fertility treatments to increase efficiency and health outcomes of ART treatments in India.
During COVID-19, like every other sector, the healthcare industry, including the IVF sector, has gone through a huge upheaval in its functioning. The European Society of Human Reproduction and Embryology, the British Fertility Society, the Centers for Disease Control and Prevention, among other medical research organizations, issued guidelines while adhering to specific rules that ensured the highest level of patient safety and personnel, such as keeping a safe distance from each other, always wearing a mask, routinely disinfecting hands and equipment, etc. Additionally, these medical research organizations advise against continuing therapy if a woman is newly diagnosed with COVID-19 while being boosted. Additionally, guidelines recommend freezing anything if the diagnosis is discovered or suspected between egg retrieval and embryo transfer.
AI in IVF
AI has the potential to improve clinical efficacy and efficacy, thereby improving the course of ART treatment. Currently, embryologists manually review images to look for a specific set of visually noticeable features. Although an experienced embryologist has limited information, the AI predictor has at least 100,000 specimens in its database. He has more experience than any doctor and can predict the future more accurately. This gives AI models the ability to examine small details that are often hard to spot even for the most skilled embryologists.
From fertilization to the blastocyst stage, AI provides real-time predictions by integrating with time-lapse imaging (TLI) technologies. Embryos at different stages of development are automatically recognized, segmented and studied at the pixel level as they are photographed by the TLI system.
Women today prioritize progressing in education or achieving professional ambitions and delay family planning. Although there is no way to stop the passage of time, assisted reproductive technology allows a person to preserve their options while providing an opportunity for personal and professional growth.
One of the most common techniques for many women to preserve their fertility is egg cryopreservation, where eggs collected from the ovaries are frozen unfertilized and stored for later use. Although a person has their healthiest eggs in their 20s and 30s, cryopreservation is an option for women of any reproductive age. The success rate for fertilizing and thawing in previous years was found to be average at best.
Laser Assisted Hatching – Laser-assisted hatching is the most advanced IVF technique. This involves creating a gap in the hard outer shell of the embryo, which facilitates implantation. In most cases of IVF, the embryo is effectively implanted in the womb.
Oocyte activation IVF- An effective way to prevent complete fertilization failure in human in vitro fertilization-embryo transfer (IVF-ET) cycles is artificial oocyte activation (AOA), where a substance called a calcium ionophore is used to help activate the egg and improve fertilisation. .
Robotic technologies and nanobots- ICSI has become more automated thanks to robotics and nanotechnology, which have made it possible to select the optimal sperm or embryo for a given situation to analyze oocyte penetration in real time. The best sperm cell is selected and transported by nanotechnology until it enters the egg, where it is then implanted to create a healthy embryo.
The increased use of IVF is due to changing demographic and cultural attitudes. ART has rapidly and significantly advanced the search for acceptable treatment options for any infertile couple. The cost and complexity of treatment are reduced to alleviate stress and social problems. The multiple dangers of pregnancy and the use of stimulated cycles have virtually been eliminated, and new approaches are currently being explored to treat severe male factor infertility and detect genetic abnormalities in the embryo prior to transfer. It is essential that medical treatment, especially reproductive care, is provided with the highest level of safety.
The views expressed above are the author’s own.
END OF ARTICLE